Generic Indic Text-to-speech Synthesisers with Rapid Adaptation in an End-to-end Framework

Building text-to-speech (TTS) synthesisers for Indian languages is a difficult task owing to a large number of active languages. Indian languages can be classified into a finite set of families, prominent among them, Indo-Aryan and Dravidian. The proposed work exploits this property to build a generic TTS system using multiple languages from the same family in an end-to-end framework. Generic systems are quite robust as they are capable of capturing a variety of phonotactics across languages. These systems are then adapted to a new language in the same family using small amounts of adaptation data. Experiments indicate that good quality TTS systems can be built using only 7 minutes of adaptation data. An average degradation mean opinion score of 3.98 is obtained for the adapted TTSes. Extensive analysis of systematic interactions between languages in the generic TTSes is carried out. x-vectors are included as speaker embedding to synthesise text in a particular speaker's voice. An interesting observation is that the prosody of the target speaker's voice is preserved. These results are quite promising as they indicate the capability of generic TTSes to handle speaker and language switching seamlessly, along with the ease of adaptation to a new language

Effect of Humic Acid on Spirulina plantisis Production and Analysis of Nutrient Contents

Spirulina is a microscopic blue-green alga in the shape of a spiral coil, used as a human dietary supplement, as well as a whole food, which was cultivated in different concentrations of humic acid such as 0.1%, to 0.7 %. The protein, chlorophyll, fatty acids levels measured at the end of the experiment in all concentrations. Among the concentration the maximum biomass was obtained from 0.2% of humic acid treated medium. The lower amount of biomass was obtained from above 0.5%.In this study, it was found that increased concentration of humic acid decreases the biomass of Spirulina plantensis. Thus it was concluded in this work, that lower concentration of humic acid increases the growth and nutrient contents of Spirulina plantensiss

A miraculous pregnancy following a myocardial infarction and coronary artery bypass grafting: a case report and review of literature

Cardiovascular disease is estimated to occur in 0.4-4.1% of pregnant women, whereas coronary heart disease complicates only 0.01% of all pregnancies. In recent times, MI has been observed to occur more frequently in young women. This might be attributed to the fact that women are deciding to become pregnant at advanced age. In such high-risk cases, proper pre-pregnancy, antenatal, intrapartum and post-partum care should be taken. Pregnant women with heart disease should be managed by a multidisciplinary team approach comprising of obstetricians, intensivists, cardiologists and neonatologists. Here, a case of pregnant woman with past history of MI; treated with coronary artery bypass grafting (CABG) is presented and the management is highlighted

ANALYSIS OF ROAD NETWORKS BY USING GEOGRAPHICAL INFORMATION SYSTEM

Transportation is one of the fastest growing of several fields where Geographic Information System software is utilized. Geographic Information System in support of transportation is rising as an important tool of planning management intended for transportation professionals. Our project mainly deals with the work that has to be done on road networks of nalgonda district which is positioned in Telangana state of India. The Geographic Information System software is mostly used in road networks analysis. The project is extremely helpful in finding of traditional routes, new routes, and for finding out of shortest distances between any two places, and so on

Dynamics of MHD Convection of Walters B Viscoelastic Fluid through an Accelerating Permeable Surface Using the Soret–Dufour Mechanism

The MHD convective Walters-B memory liquid flow past a permeable accelerating surface with the mechanism of Soret-Dufour is considered. The flow equation constitutes a set of partial differential equations (PDEs) to elucidate the real flow of a non-Newtonian liquid. The radiation thermo-physical parameters were employed based on the use of Roseland approximation. This implies the fluid employed in this exploration is optically thick. Utilizing suitable similarity terms, the flow equation PDEs were simplified to become total differential equations. The spectral homotopy analysis method (SHAM) was utilized to provide outcomes to the model. The SHAM involves the addition of the Chebyshev pseudospectral approach (CPM) alongside the homotopy analysis approach (HAM). The outcomes were depicted utilizing graphs and tables for the quantities of engineering concern. The mechanisms of Soret and Dufour were separately examined. The imposed magnetism was found to lessen the velocity plot while the thermal radiation term elevates the temperature plot because of the warm particles of the fluid.This research was funded by a grant of the Romanian Ministry of Research, Innovation and Digitalization, project number PFE 26/30.12.2021, PERFORM-CDI@UPT100—The increasing of the performance of the Polytechnic University of Timis, oara by strengthening the research, development and technological transfer capacity in the field of “Energy, Environment and Climate Change” at the beginning of the second century of its existence, within Program 1—Development of the national system of Research and Development, Subprogram 1.2—Institutional Performance—Institutional Development Projects—Excellence Funding Projects in RDI, PNCDI III.info:eu-repo/semantics/publishedVersio

Dynamic Phenotypic Switching and Group Behavior Help Non-Small Cell Lung Cancer Cells Evade Chemotherapy

Drug resistance, a major challenge in cancer therapy, is typically attributed to mutations and genetic heterogeneity. Emerging evidence suggests that dynamic cellular interactions and group behavior also contribute to drug resistance. However, the underlying mechanisms remain poorly understood. Here, we present a new mathematical approach with game theoretical underpinnings that we developed to model real-time growth data of non-small cell lung cancer (NSCLC) cells and discern patterns in response to treatment with cisplatin. We show that the cisplatin-sensitive and cisplatin-tolerant NSCLC cells, when co-cultured in the absence or presence of the drug, display dynamic group behavior strategies. Tolerant cells exhibit a \u27persister-like\u27 behavior and are attenuated by sensitive cells; they also appear to \u27educate\u27 sensitive cells to evade chemotherapy. Further, tolerant cells can switch phenotypes to become sensitive, especially at low cisplatin concentrations. Finally, switching treatment from continuous to an intermittent regimen can attenuate the emergence of tolerant cells, suggesting that intermittent chemotherapy may improve outcomes in lung cancer

Technology Pipeline for Large Scale Cross-Lingual Dubbing of Lecture Videos into Multiple Indian Languages

Cross-lingual dubbing of lecture videos requires the transcription of the original audio, correction and removal of disfluencies, domain term discovery, text-to-text translation into the target language, chunking of text using target language rhythm, text-to-speech synthesis followed by isochronous lipsyncing to the original video. This task becomes challenging when the source and target languages belong to different language families, resulting in differences in generated audio duration. This is further compounded by the original speaker's rhythm, especially for extempore speech. This paper describes the challenges in regenerating English lecture videos in Indian languages semi-automatically. A prototype is developed for dubbing lectures into 9 Indian languages. A mean-opinion-score (MOS) is obtained for two languages, Hindi and Tamil, on two different courses. The output video is compared with the original video in terms of MOS (1-5) and lip synchronisation with scores of 4.09 and 3.74, respectively. The human effort also reduces by 75%